Skip to content

Assessment the efficacy of rotator cuff injection of Platelet Rich Plasma in patients with partial tear of rotator cuff

A randomized controlled trial, Comparing the effectiveness of ultrasound guided injection of Platelet Rich Plasma and shoulder physiotherapy on pain and function of patients with partial-thickness rotator cuff tears

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011205214N1
Enrollment
40
Registered
2011-06-14
Start date
2010-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator cuff tendon tear. Rotator cuff syndrome

Interventions

Intervention 1: Patient in Intervention group, will refer to blood transfer institute and in there ,venous blood samples (50 ml) will be collected from an antecubital vein. After two-centrifugation st
Treatment - Drugs
Rehabilitation
Patient in Intervention group, will refer to blood transfer institute and in there ,venous blood samples (50 ml) will be collected from an antecubital vein. After two-centrifugation step at least 3 ml
Control group:will receive 15 session shoulder physiotherapy

Sponsors

Vice chancellor for research Tehran university of medical science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria include: established rotator cuff tear (traumatic or degenerative) in MRI that should not be massive or full thickness in the radiologist report; shoulder pain or dysfunction in a severity level that patient look for medical intervention or candidate for surgery; all patients should have failed two-week treatments with NSAIDs and six weeks of physical therapy; Written informed consent. The exclusion criteria include: pregnancy or active breast-feeding; presence of a tumor, metastatic disease, active infections; platelet count less than 100000 per µl or Hgb less than 10 g/dl; gross instability of the glenohumeral joint; superior labral lesions requiring surgical repair; patients with painful cervical spine pathology; previous surgery on the shoulder joint; national or international level athletes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: before intervention, 4 weeks, 8weeks and 12weeks after intervention. Method of measurement: 10cm VAS.;Function. Timepoint: Before intervention, 4 weeks ,8weeks and 12weeks after intervention. Method of measurement: Constant score.

Secondary

MeasureTime frame
Quality of life. Timepoint: Before intervention, and 4 weeks ,8weeks and 12weeks after intervention. Method of measurement: WORC.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Elham Eamani

The Sports and Exercise Medicine Research Centre, the Tehran University of Medical Sciences

ezamani@tums.ac.ir+98 21 8863 0227

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026