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Comparison of efficacy of ketamine and tramadol in preventing post-operative shivering

A comparison of efficacy of intravenous ketamine and tramadol in preventing post-operative shivering in general anesthetic patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011164819N2
Enrollment
150
Registered
2011-07-27
Start date
2011-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post_operative shivering. Other complications of anaesthesia

Interventions

Intervention 1: In second group, 30 min. before finishing anesthesia we will inject 0.5 mg/kg of ketamine intravenusely. Intervention 2: In third group, we will inject 2 cc N/S IV, 30 min. before fini
Treatment - Drugs
Placebo
In second group, 30 min. before finishing anesthesia we will inject 0.5 mg/kg of ketamine intravenusely
In third group, we will inject 2 cc N/S IV, 30 min. before finishing anesthesia.
In First group, we will inject 0.3 mg/kg of tramadol IV, 30 min. before finishing anesthesia.

Sponsors

Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Aged between 18 and 65; BMI less than 30; No history of seizur or multiple allergia; No history of cardiovascular diseases HTN Exclusion criteria: needs to blood or blood supply transfusion during surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Tympanic temperatur. Timepoint: Before induction of anesthesia - After induction of anesthesia - 30 min. after induction of anesthesia - At the time of entering to recovery - 15 min. after - 30 min. after. Method of measurement: With digital tympanic thermometer.;Axillary temperature. Timepoint: Before induction of anesthesia - After induction of anesthesia - 30 min. after induction of anesthesia - At the time of entering to recovery - 15 min. after - 30 min. after. Method of measurement: Mercuric Thermometer.

Secondary

MeasureTime frame
Headache. Timepoint: In recovery room. Method of measurement: Observation & asking the patient.;Halucination. Timepoint: In recovery room. Method of measurement: Observation.;Recovery stay time. Timepoint: End of recovery stay. Method of measurement: Minute.;VAS Score of pain. Timepoint: At entering to recovery - 15 min. later - 30 min. later. Method of measurement: VAS Score bethween 0-10.;VAS Score of nausea. Timepoint: In recovery room - During 24 hours later. Method of measurement: VAS Score of nausea bethween 0-10.;Vomiting. Timepoint: In recovery room - During 24 hours later. Method of measurement: Frequency.;Dizziness. Timepoint: In recovery room. Method of measurement: Observation & asking the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Saied Morteza Heidari Tabaei Zavareh

Isfahan University of Medical Sciences

m_heidari@med.mui.ac.ir+98 31 1668 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026