knee OA. Primary gonarthrosis, bilateral
Conditions
Interventions
Intervention 1: Sesame powder, 40 grams daily, for 2 months as well as physiotherapy (20 an-hour sessions for both knees), Acetaminophen 500mg twice a day, and Glucosamine one tablet daily for two mon
Treatment - Other
Treatment - Drugs
Sesame powder, 40 grams daily, for 2 months as well as physiotherapy (20 an-hour sessions for both knees), Acetaminophen 500mg twice a day, and Glucosamine one tablet daily for two months
Physiotherapy (20 an-hour sessions for both knees) as well as Acetaminophen 500mg twice a day and Glucosamine one tablet daily for two months
Sponsors
Tabriz University of Medical Sciences and Health Services
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 50-70years old, primary bilateral knee osteoarthritis based on ACR criteria, ability to consume and sesame Exclusion criteria: grade IV osteoarthritis, secondary OA, active synovitis, knee surgery or intra-articular injection, neuromuscular diseases, diabetes, metabolic diseases, cardiovascular diseases, hepatic diseases, smoking, alcohol, vitamin, and mineral supplement consumption, MI
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Markers of Lipidemia. Timepoint: Before and after the intervention. Method of measurement: Espectrophotometry(mg/dl).;Clinical sign. Timepoint: Before and after the intervention. Method of measurement: physical assessment.;Timed up and go test. Timepoint: Before and after the intervention. Method of measurement: based on walking time.;Hs-CRP. Timepoint: Before and after the intervention. Method of measurement: Imonoturbidometry.;Koos questionnaire. Timepoint: before and after intervention. Method of measurement: Koos questionnaire.;Inflammatory markers (IL-6). Timepoint: Before and after the intervention. Method of measurement: Elisa. | — |
Secondary
| Measure | Time frame |
|---|---|
| GPX. Timepoint: Before and after the intervention. Method of measurement: u/gr Hemoglubin- spectrophotometry.;SOD. Timepoint: Before and after the intervention. Method of measurement: spectrophotometry.;MDA. Timepoint: Before and after the intervention. Method of measurement: spectrophotometry.;Total Antioxidant. Timepoint: Before and after the intervention. Method of measurement: spectrophotometry. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed