Female Infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: Cinal-F, 150units, is injected subcutaneously, on the 2nd day of the cycle. The protocol is long-acting suppression with superfact. HCG 10000u is injected when ther
Sponsors
Cinajen Company
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Age less than35 years FSH in the 2 date of cycle less than or equal to8.3 regularity of menses long protocol for suppression of hypothesis
Exclusion criteria
Exclusion criteria: smoking history of any operation of ovary sensitivity to Gonal–f or Cinal-f Abnormal hormonal profiles History of ovarian hyper stimulation Tumors of sex organs Uncontrolled insufficiency of thyroid or adrenal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of metaphase II oocytes. Timepoint: The oocyte retrieval day. Method of measurement: Based on embryologist assessment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of oocyte MetaphaseI. Timepoint: At the day of OPU. Method of measurement: By the embryologist.;Evaluation of Polar Body. Timepoint: At the day of OPU. Method of measurement: By the embryologist.;Evaluation of atretic oocyte. Timepoint: At the day of OPU. Method of measurement: By the embryologist.;Evaluation of Germinal Vesicle. Timepoint: At the day of OPU. Method of measurement: By the embryologist.;Evaluation of Zona Plucida appearance. Timepoint: At the day of OPU. Method of measurement: By the embryologist.;Number of follicle stimulating hormone (FSH) vials used during stimulation. Timepoint: The oocyte retrieval day. Method of measurement: Counting of vials.;Embryo quality. Timepoint: 2-3 days after oocytes fertilization. Method of measurement: Based on embryologist assessment.;• Duration of Follicle stimulating hormone ( FSH) stimulation. Timepoint: The end of ovarian stimulation. Method of measurement: Counting of stimulation days.;Number of embryos replaced or frozen. Timepoint: 2-3 days after oocytes fertilization. Method of measurement: Counting of replaced or frozen embryos.;Number of clinical pregnancies. Timepoint: After 5-8 weeks of gestation. Method of measurement: Visualization of one or more gestational sacs in the sonography.;Number of ongoing pregnancies. Timepoint: After =20 completed weeks of gestation. Method of measurement: Detection of fetus with heart activity beyond 20 weeks of gestation by sonography.;The incidence of ovarian hyper stimulation syndrome(OHSS). Timepoint: Throughout the study. Method of measurement: Base on physician assessment according to OHSS diagnosis criteria. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBatool Hossein Rashidi
Tehran University of Medical Sciences
Outcome results
None listed