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Effect of familiar olfactory stimulation on responses to pain of blood sampling in neonates

Effect of familiar olfactory stimulation on responses to pain of blood sampling in neonates

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011135163N1
Enrollment
135
Registered
2010-12-01
Start date
2009-04-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal pain. Acute pain

Interventions

Intervention 1: For the familiar odor group, familiarization will be performed the night before blood sampling and neonates will be exposed to the vanillin odor during the painful procedure. In this g
Prevention
Treatment - Drugs
Control group: no intervention
For neonates in the unfamiliar group, the familiarization will not be carried out but blood sampling will be done in the presence of the vanillin odor 0/64%.
For the familiar odor group, familiarization will be performed the night before blood sampling and neonates will be exposed to the vanillin odor during the painful procedure. In this group, a sterile

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 1-7 days, 37-42 weeks of gestational age at birth, no neurologic, cardiologic or respiratory impairments or congenital anomalies Exclusion criteria: restlessness before the procedure, receiving sedatives or analgesics for 24 hours before the procedure, neonates in whom, the first needling for blood sampling was not successful

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
O2 Saturation. Timepoint: two minutes prior to sampling, after inserting and removing the needle. Method of measurement: pulse oximeter.;Heart Rate. Timepoint: two minutes prior to sampling, after inserting and removing the needle. Method of measurement: Pulse oximeter.

Secondary

MeasureTime frame
Crying duration. Timepoint: from onset until a crying free interval of more than five seconds. Method of measurement: voice recording.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAkram sadat Sadat Hoseini

Tehran University of Medical Sciences

ashoseini@tums.ac.irashoseini@modares.ac.ir+98 21 6692 7171

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026