Effect of ?-3 fatty acids on gastric cancer patients

Study on the effect of ?-3 fatty acids supplementation on nutritional status, some inflammatory factors and matrix metalloproteinases in gastric cancer patients undergoing chemotherapy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201011095144N1

Enrollment

Registered

2011-01-28

Start date

2010-05-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer patients undergoing chemotherapy. Malignant neoplasm of stomach

Interventions

Intervention 1: Interventions 1: ?-3 fatty acids, 3 g daily for 45 days. Intervention 2: interventions2: rice powder, three capsules daily for 45 days.

Treatment - Drugs

Placebo

Interventions 1: ?-3 fatty acids, 3 g daily for 45 days

interventions2: rice powder, three capsules daily for 45 days

Eligibility

Sex/Gender

All

Age

30 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with gastric cancer in phase 3 (cardia and non cardia) during chemotherapy over 30 years old. Exclusion criteria: other diseases induced cachexia such as heart disease, lung, AIDS, renal disease, incidence of acute leukemia, diabetes and multiple myeloma, individauls undergoing surgery and who do not take the given drugs properly during the study period.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Weight. Timepoint: days of 0, 30 and 45. Method of measurement: digital scale.	—

Secondary

Measure	Time frame
Body Mass Index. Timepoint: days of 0, 30 and 45. Method of measurement: measured by ratio of weight (kilograms) to squared height (m).;Daily calorie intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire.;Daily nutreints intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire.;Nausea. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Vomiting. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Appetite. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Dairreha. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnare.;Abdominal cramp. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Total antioxidant. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry.;MDA. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry.;Interleukin1. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Interleukin 6. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Interleukin 2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;TNF-?. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Mmp9. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Mmp2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Cholestrol. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Triglyceride. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;TIBC. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Blood albumin. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;LDL- C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;HDL-C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Blood iron. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;CRP. Timepoint: days of 0, 30 and 45. Method of meas	—

Measure

Time frame

Body Mass Index. Timepoint: days of 0, 30 and 45. Method of measurement: measured by ratio of weight (kilograms) to squared height (m).;Daily calorie intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire.;Daily nutreints intake. Timepoint: days of 0, 30 and 45. Method of measurement: 24 hour recall questionnaire.;Nausea. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Vomiting. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Appetite. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Dairreha. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnare.;Abdominal cramp. Timepoint: days of 0, 30 and 45. Method of measurement: quaistionnaire.;Total antioxidant. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry.;MDA. Timepoint: days of 0, 30 and 45. Method of measurement: spectrophotometry.;Interleukin1. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Interleukin 6. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Interleukin 2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;TNF-?. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Mmp9. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Mmp2. Timepoint: days of 0, 30 and 45. Method of measurement: ELISA.;Cholestrol. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Triglyceride. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;TIBC. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Blood albumin. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;LDL- C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;HDL-C. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;Blood iron. Timepoint: days of 0, 30 and 45. Method of measurement: autoanalyzer.;CRP. Timepoint: days of 0, 30 and 45. Method of meas

—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026