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The effect of insulin therapy on outcome of critically ill patients

The effect of insulin therapy on morbidity and mortality of critically ill patients admitted to intensive care unit

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011062582N1
Enrollment
60
Registered
2010-12-08
Start date
2010-11-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

External causes of morbidity and mortality. Hyperglycaemia, unspecified

Interventions

Intervention 1: Intervention group will recieve insulin drip based on following formula: (BS-120) / 20. For hypoglycemic events insulin drip will be hold and patients will receive Dextrose Water 50% b
Treatment - Drugs
Intervention group will recieve insulin drip based on following formula: (BS-120) / 20. For hypoglycemic events insulin drip will be hold and patients will receive Dextrose Water 50% based on the form
In Control group: patients receive bolus doses of insulin only in blood glucose more than 200 mg/dl based on the following formula: (BS-180)/30. Blood glucose will be monitored three times daily.

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 81 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: adult (more than 18 y.o) critically ill patients who admitted to surgical ICU (Intensive Care Unit). Exclusion criteria: Patients with Intensive Care Unit length of stay less than 3 days, patients who can tolerate oral feeding, patients with DNR (DO NOT RESSUSCITATE) order.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Mortality. Timepoint: Daily, during the ICU stay. Method of measurement: physical exam.

Secondary

MeasureTime frame
Morbidity (Acute Kidney Injury, Transfusion requirement, bactremia, hypoglycemia). Timepoint: Daily, during the ICU stay. Method of measurement: Creatinine increasing for Acute Kidney Injury, Number of packed cell which is transfused for transfusion requirement, positive blood culture and systemic inflammatory response syndrome for bacteremia, blood glucose less than 60 mg/dl as hypoglycemia.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Ostadrahimi

Tabriz University of Medical Sciences

aostadrahimi@yahoo.com+98 41 1335 7311

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026