The effect of vitamin C in the treatment of pneumonia

Investigating the effect of vitamin C administration on improving pneumonia in children 2 to 12 years of age

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101106005114N3

Enrollment

100

Registered

2020-06-18

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Unspecified bacterial pneumonia

Interventions

Intervention 1: Intervention group: receiving a single dose of vitamin C 500 mg. Intervention 2: Control group:receiving placebo as a single dose and in terms of drug form is quite similar to vitamin

Eligibility

Sex/Gender

All

Age

2 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children 2 to 12 years of age who have been given a definitive diagnosis of pneumonia according to clinical signs and graphics

Exclusion criteria

Exclusion criteria: Existence of underlying disease such as cystic fibrosis, bronchiectasis, acute or chronic kidney disease Vitamin C intake over the past 1 month The patient is intubated

Design outcomes

Primary

Measure	Time frame
Evaluation of fever every 6 hours by the evaluator and registration in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Assessment of fever through an axillary thermometer.;Evaluate the number of breaths every 6 hours by the evaluator and record in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Evaluation of the number of breaths through clinical examination and counting the number of breaths per minute by the evaluator and registration in the file.;Evaluation of Oxygen saturation level every 6 hours by the evaluator and record in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Evaluation of oxygen saturation level through oximeter pulse by the evaluator and registration in the file.	—

Measure

Time frame

Evaluation of fever every 6 hours by the evaluator and registration in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Assessment of fever through an axillary thermometer.;Evaluate the number of breaths every 6 hours by the evaluator and record in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Evaluation of the number of breaths through clinical examination and counting the number of breaths per minute by the evaluator and registration in the file.;Evaluation of Oxygen saturation level every 6 hours by the evaluator and record in the file. Timepoint: 6? 12? 18? 24? 30? 36? 42? 48? 54? 60 hours. Method of measurement: Evaluation of oxygen saturation level through oximeter pulse by the evaluator and registration in the file.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Heydarian

Mashhad University of Medical Sciences

HeydarianF@mums.ac.ir+98 51 3726 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026