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The effect of quercetin supplementation in women with type 2 diabetes

Study of quercetin supplementation on risk factors for cardiovascular disease, inflammatory biomarkers and oxidative stress and the relationship between physical activity level in women with type 2 diabetes

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201011015062N1
Enrollment
72
Registered
2011-12-07
Start date
2011-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes. Non-insulin dependent type2 diabetes

Interventions

Intervention 1: The intervention group received daily 500mg capsule quercetin for 10 weeks. Intervention 2: control group received 500mg placebo(lactose) daily for 10 weeks.
Treatment - Other
Placebo
The intervention group received daily 500mg capsule quercetin for 10 weeks
control group received 500mg placebo(lactose) daily for 10 weeks

Sponsors

Research Deputy of Isfahan University of Medical Sciences field
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
35 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1. Willingness to participate in the study 2. Type 2 diabetes diagnosed by a physician 3. Having a history of diabetes at least 3 years 4. Age between 35-55 years 5. Not smoking and addiction 6. Lack of severe heart disease, stroke, liver disease, renal, gastrointestinal, thyroid, parathyroid, rheumatoid arthritis and infectious disease 7. Lack of insulin 8. Lack of antioxidant supplements in the previous month 9. Lack of pregnancy and lactation Exclusion criteria 1. Need to change the dose and type of drug from the baseline to the end 2. Occurring in pregnancy 3. Less than 70% adherence 4. Unwillingness to continue reading 5. Staying beyond the fixed type and dose of drugs during the intervention. 6. There are diseases that require special treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: befor start and end of study. Method of measurement: Mercury Barometer - mmHg.;Total Cholesterol. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;HDL-c. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;LDL-c. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;TG. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;FBS. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;HbA1c. Timepoint: befor start and end of study. Method of measurement: Enzymatically-mg/dl.;MDA. Timepoint: befor start and end of study. Method of measurement: ELISA-ng/ml.;Total antioxidant capacity. Timepoint: befor start and end of study. Method of measurement: Chemical colorimetric-mmol/L.;TNF-a. Timepoint: befor start and end of study. Method of measurement: ELISA-pg/ml.;Hs-CRP. Timepoint: befor start and end of study. Method of measurement: ELISA-mg/L.;IL-6. Timepoint: befor start and end of study. Method of measurement: ELISA-pg/ml.;Diastolic blood pressure. Timepoint: befor start and end of study. Method of measurement: Mercury Barometer - mmHg.

Secondary

MeasureTime frame
Physical Activity. Timepoint: before start and end of sudy. Method of measurement: IPAQ Questionnaire-Met.minutes/week.;Weight. Timepoint: before start and end of sudy. Method of measurement: Weight gauge-Kg.;Food intake. Timepoint: First, the fifth week, the tenth week. Method of measurement: Inventory Software N4.;The waist to hip circumference. Timepoint: before start and end of sudy. Method of measurement: Tape-Centimeter.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026