The effect of intravenous Tranexamic acid on blood loss and the quality of surgical field during endoscopic sinus surgery

The effect of intravenous Tranexamic acid on blood loss and the quality of surgical field during endoscopic sinus surgery: A placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201010265026N1

Enrollment

Registered

2011-02-21

Start date

2009-04-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemorrhagic condition. Haemorrhagic condition, unspecified

Interventions

Intervention 1: intravenous tranexamic acid (10 mg/kg as a bolus dose immediately after induction of anesthesia). Intervention 2: Placebo (sterile water 0.1cc/kg as a bolus dose immediately after indu

Treatment - Drugs

Placebo

intravenous tranexamic acid (10 mg/kg as a bolus dose immediately after induction of anesthesia)

Placebo (sterile water 0.1cc/kg as a bolus dose immediately after induction of anesthesia)

Eligibility

Sex/Gender

All

Age

19 Years to 64 Years

Inclusion criteria

Inclusion criteria: inclusion: ASA physical status I-II patients candidate of endoscopic sinus surgery for chronic sinusitis Exclusion: Patients receiving anticoagulants or having a bleeding diathesis

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Blood presssure, heart rate. Timepoint: q 15 minutes. Method of measurement: data collected from standard operting room monitoring systems.	—

Primary

Measure	Time frame
The quality of surgical field. Timepoint: at the end of surgery. Method of measurement: Standardized scale.;Blood loss. Timepoint: at the end of surgery. Method of measurement: visual estimation of blood loss in bottles.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahzad Alimian

Department of Anesthesiology, Tehran University of Medical Sciences

Alimian.mahzad@gmail.com+98 216432326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026