Parkinson disease. Hemiparkinsonism Paralysis agitans Parkinsonism or Parkinson disease: NOS idiopathic primary
Conditions
Interventions
Intervention 1: Propofol 30 microgram/kg for maintenace of anesthesia. Intervention 2: Sevoflourane 1% for maintenance of anesthesia.
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with Advanced Parkinson's Patients with severe dyskinesia due to levodopa administration
Exclusion criteria
Exclusion criteria: Severe cardiovascular or ischemic diseases Uncontrolled hypertension CVA Cancer or any life-threatening agent Taking anti-coagulants Severe psychiatric disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of recovery from anesthetics. Timepoint: During the targeting of subthalamic nucleus. Method of measurement: Minutes using a chronometer.;Blood pressure. Timepoint: Every 5 minutes during the maintenance of anesthesia. Method of measurement: Automatic noninvasive sphyngometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: Before induction, half an hour after induction, before discontinuation of anesthetics, during neurological examination every 15 minutes, at the end of surgery. Method of measurement: Continuous ECG monitoring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasood mohseni
Iran University of Medical Sciences
Outcome results
None listed