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The Effect of Remifentanil or Fentanyl on Postoprative Nausea and Vomiting after Cesarean Section

The Effect of Remifentanil or Fentanyl on Postoprative Nausea and Vomiting after Cesarean Section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT201010232405N5
Enrollment
96
Registered
2010-12-18
Start date
2005-02-16
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of anaesthesia during pregnancy. Other complications of anaesthesia during pregnancy

Interventions

Intervention 1: Remifentanil injection (0.05 microg /kg/h) intravenously, Duration of treatment: time from after clamping of umbilical cord to completion of surgery. Intervention 2: Fentanyl 2 microg/
Treatment - Drugs
Remifentanil injection (0.05 microg /kg/h) intravenously, Duration of treatment: time from after clamping of umbilical cord to completion of surgery
Fentanyl 2 microg/kg pulse morphin 0.1mg/kg intravenously, Duration of treatment: time from after clamping of umbilical cord to completion of surgery
Fentanyl injection (2 microg/kg/h) intravenously, Duration of treatment: time from after clamping of umbilical cord to completion of surgery

Sponsors

Medical School, Isfahan University of Medical Scienes,
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
16 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Parturients, ASA physical status I-II, scheduled for elective cesarean section, under general anesthesia Exclusion Criteria: Allergy to fentanyl or remifentanil, atopia, diabetes mellitus, presence of liver or kidney diseases, drugs abuse, presence of complicated pregnancy such as hypertension or preeclampsia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea intensity. Timepoint: at recovery, 4, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analogous Scale (VAS) and scoring from 0 to 10.;Frequency of PONV. Timepoint: at recovery, 4, 8, 12 and 24 hours after surgery. Method of measurement: counting.

Secondary

MeasureTime frame
Pain intensity. Timepoint: at recovery, 4, 8, 12 and 24 hours after surgery. Method of measurement: Visual Analogous Scale (VAS) and scoring from 0 to 10.;Opioid consumption. Timepoint: at recovery, 4, 8, 12 and 24 hours after surgery. Method of measurement: in miligram of opioid.;Metoclopramide consumption. Timepoint: at recovery, 4, 8, 12 and 24 hours after surgery. Method of measurement: in miligram of drug.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mitra Jabalameli

Isfahan University of Medical Sciences

jabalameli@med.mui.ac.ir+98 31 1236 3600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026