Atopic Dermatitis. infantile (acute)(chronic)
Conditions
Interventions
Intervention 1: Participants were randomly divided into two groups.
Intervention: Patients in the probiotic group received synbiotic containing 1 billion Colony Forming Unit(CFU) of Protexin Restore:
Treatment - Drugs
Participants were randomly divided into two groups.
Intervention: Patients in the probiotic group received synbiotic containing 1 billion Colony Forming Unit(CFU) of Protexin Restore: a mixture of L
CONTROL: The control group received placebo powder without probiotics which were matched for size, shape, and volume of contents and manufactured by the same company, twice daily for 8 weeks
Sponsors
vice chancellor for research, Mashhad University of medical sciences.
Eligibility
Sex/Gender
All
Age
No minimum to 6 Years
Inclusion criteria
Inclusion criteria: Inclusion: Aged from 3 months to 6 years Mild to severe Atopic dermatitis Exclusion: Prior exposure to probiotics Were currently taking a course of antibiotics, or had other major medical problems
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Atopic Dermatitis. Timepoint: At the beginning of the study, 2 months after intervention. Method of measurement: SCORAD method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokine profile(IL-4, INF- Gamma ). Timepoint: At the beginning of the study, 2 months after intervention. Method of measurement: ELISA on supernatant of Blood lymphocyte culture. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed