lower leg fracture. Multiple fractures of lower leg
Conditions
Interventions
Intervention 1: no premedication. Intervention 2: 200 mg celecoxib the night before surgery and 200 mg in the morning. Intervention 3: 400mg celecoxib night before surgery.
Prevention
200 mg celecoxib the night before surgery and 200 mg in the morning
400mg celecoxib night before surgery
Sponsors
Tehran University of Medical Science
Eligibility
Sex/Gender
All
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 20-40 y ASA I , II patients candidated for leg fracture operation, without history of opium addiction, no history of cardiac disease and previous cardiac problems (MI , CAD ), no history of CVA, no previous analgesic consumption, Exclusion criteria : analgesic consumption prior premedication, time of surgery more than 3 h , multiple trauma
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain after leg fracture surgery. Timepoint: immediately at the end of operation - 2,4,6h after surgery. Method of measurement: visual analogue scale , 1 to 10. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of analgesic request by the patient. Timepoint: the first time patient asked for analgesuic. Method of measurement: hour after surgery.;Amount of opium injected to patient during 24 h. Timepoint: at the end of first day after surgery. Method of measurement: miligram of opium consumpted. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed