Effect of 6 weeks of neuromuscular exercise on knee varus thrust, muscle activity and pain during descending the stairs in people with early knee osteoarthritis with varus thrust

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101017004952N12

Enrollment

Registered

2024-05-10

Start date

2024-06-21

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early knee osteoarthritis. Primary generalized (osteo)arthritis

Interventions

Intervention 1: Control group: In this group, the traditional exercises for people with knee osteoarthritis, namely strengthening the quadriceps muscle, will be performed in the form of quadriceps se

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Early knee osteoarthritis (grade 1-2) - Presence of varus thrust in the knee - BMI (body mass index) between 22 and 30 - The ability to go down the stairs without an aid - radiographic control and rejection of other lower limb musculoskeletal injuries

Exclusion criteria

Exclusion criteria: - Other musculoskeletal diseases and damage to lower limb joints (such as rheumatic diseases, neuropathy, diabetic neuropathy) - Neuromuscular diseases (such as Parkinson's, hemiplegia, multiple sclerosis) - Genovalgom more than 5 degrees and genovarum more than 10 degrees - History of knee joint surgery - History of joint injections during the last 6 months - A history of cardio-respiratory disorders that prevent therapeutic exercises. - The patient can withdraw from the study at any stage and for any reason, if he does not want to cooperate.

Design outcomes

Primary

Measure	Time frame
Knee adduction excursion. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: The difference between the knee adduction angle at the moment of heel contact and the maximum knee adduction angle during the stance phase with a 3D motion capture device.;Pain. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using Visual Analogue Scale (VAS) and WOMAC questionnaire.;Quadriceps, hamstring and gastrocnemius muscle activity. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using electromyography system.;Knee adduction velocity. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Change of knee adduction angle per unit of time with a 3D motion capture device.;External moments of the knee joint. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: During step-down, the knee moments were measured through the inverse dynamics method and using a three-dimensional motion capture system.;Strength of knee flexor and extensor and hip abductor muscles. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using a digital hand-held dynamometer and through MMT, the muscle strength of knee flexor and extensor and hip abductor will be measured.	—

Measure

Time frame

Knee adduction excursion. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: The difference between the knee adduction angle at the moment of heel contact and the maximum knee adduction angle during the stance phase with a 3D motion capture device.;Pain. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using Visual Analogue Scale (VAS) and WOMAC questionnaire.;Quadriceps, hamstring and gastrocnemius muscle activity. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using electromyography system.;Knee adduction velocity. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Change of knee adduction angle per unit of time with a 3D motion capture device.;External moments of the knee joint. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: During step-down, the knee moments were measured through the inverse dynamics method and using a three-dimensional motion capture system.;Strength of knee flexor and extensor and hip abductor muscles. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: Using a digital hand-held dynamometer and through MMT, the muscle strength of knee flexor and extensor and hip abductor will be measured.

—

Secondary

Measure	Time frame
Displacement and velocity of the center of pressure sway. Timepoint: Beginning and end of 6 weeks of therapeutic exercise. Method of measurement: During 20 seconds of a double stance on the force plate.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGiti Torkaman

Tarbiat Modares University

torkamang@yahoo.com+98 21 8288 4509

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026