Effect of exercise therapy with and without intra-articular hyaluronic acid in knee osteoarthritis

Effect of exercise therapy with and without intra-articular hyaluronic acid injection on the COP sway and its location in the base of support and physical function in patients with knee osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20101017004952N10

Enrollment

Registered

2020-01-03

Start date

2016-11-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis

Interventions

Intervention 1: Group intervention 1: Conventional exercise therapy and 3 intra-articular injection of Hyalgan in knee osteoarthritis patients (n=12). Intervention 2: Group intervention 2: three intra

Eligibility

Sex/Gender

All

Age

45 Years to 70 Years

Inclusion criteria

Inclusion criteria: grade II or III of OA based on Kellgren-Lawrence the ages of 45 and 70 year Primary symptomatic knee osteoarthritis for at least 6 between No other treatments for 6 months prior to the study Pain for at least 3 months Muscle strength at least 3 using dynamometer

Exclusion criteria

Exclusion criteria: osteoporosis Participating muscle strengthening plan at least for 3 months ago Meniscal lesions Lower limb surgery Hard flat foot Knee valgus>15 and knee varus> 10 Corticosteroid injection in 6 months ago Suffering any other arthritis Serious systemic or nervous disease Visual disturbance Vestibular, neurologic, neuromuscular & chronic orthopedic disease Joint injury Severe muscle weakness

Design outcomes

Primary

Measure	Time frame
Balance,center of pressure sway. Timepoint: before and 5 weeks after the beginning of the treatment. Method of measurement: Force plate.;CoP location in base of support. Timepoint: before and 5 weeks after the beginning of the treatment. Method of measurement: Force plate.	—

Secondary

Measure	Time frame
Quality of life. Timepoint: before and 5 weeks after the beginning of the treatment. Method of measurement: SF-36, WOMAC.;Functional activity. Timepoint: before and 5 weeks after the beginning of the treatment. Method of measurement: 6-min walk, timed up and go, star excursion, 8-walking test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGiti Torkaman

Tarbiat Modares university

torkamg@modares.ac.ir+98 21 8288 4509

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026