Survey and comparison of the efficacy of Kytril®, Granisetron and Metoclopramide in control of postoperative nausea and vomiting

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201010134927N1

Enrollment

150

Registered

2011-03-11

Start date

2010-02-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting. Postprocedural disorder of digestive system, unspecified

Interventions

Intervention 1: Kytril 40mcg/kg/day I.V. up to 18h after operation. Intervention 2: Granisetron 40mcg/kg/day I.V. up to 18h after operation. Intervention 3: Metoclopramide 0.2mcg/kg/day I.V. up to 18h

Treatment - Drugs

Kytril 40mcg/kg/day I.V. up to 18h after operation

Granisetron 40mcg/kg/day I.V. up to 18h after operation

Metoclopramide 0.2mcg/kg/day I.V. up to 18h after operation

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: female patients undergoing a surgery Exclusion criteria: presence of gastrointestinal tract disorders, motion sickness, post-operation nausea and vomiting; having received anti emetics during 24 hours prior to the surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Vomiting. Timepoint: 6 hours. Method of measurement: Physical examination.;Nausea. Timepoint: 6 hours. Method of measurement: Physical examination.	—

Secondary

Measure	Time frame
Sedation. Timepoint: One time. Method of measurement: Physical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ashraf Alyasin

Dr. Shariati Teaching Hospital

alyasina@sina.tums.ac.ir+98 21 8490 2421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 22, 2026