Condition 1: Moderate depression. Condition 2: Mild depression. Moderate depressive episode Mild depressive episode
Conditions
Interventions
Intervention 1: Tricyclic antidepressant with average dose, as well as Hypericum Perforatum (a herbal formulation), three times a day 6 weeks. Intervention 2: Tricyclic antidepressant with average dos
Treatment - Drugs
Placebo
Tricyclic antidepressant with average dose, as well as Hypericum Perforatum (a herbal formulation), three times a day 6 weeks
Tricyclic antidepressant with average dose, as well as placebo, three times a day 6 weeks
Sponsors
Vice-chancellor for Research, Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Major depressive disorder diagnosed by a psychiatrist based on DSM-IV-TR criteria, age range between 18-55 years, filling the consent form, mild or moderate severity of depression Exclusion Criteria: Pregnancy, breast feeding, organic or neurological disorder featuring both clinically, Axis II psychiatric disorder, presence of simultaneous psychiatric disorder diagnosis in axis I, using alcohol and other addictive substances other than nicotine and caffeine in a one-month past, exacerbation of symptoms of severe depression or psychotic disorders, Signs that require hospitalization and emergency action such as suicidal thoughts and behaviors, Not receiving ECT over three months prior to the study, any particular sensitivity to plant grass herbal tea, consumption of medicine such as lithium, anticonvulsants, sumatriptan, Al Biped, serotonin-reuptake inhibitors, buspirone, Argo compounds, Selegiline, stimulants, anti-congestive, contraceptives, cimetidine, theophylline or thyroid hormones during 7 days prior to the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of sleep. Timepoint: 3 weeks. Method of measurement: clinical interview.;Improvement of apetite. Timepoint: 3 weeks. Method of measurement: clinical interview. | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment of depression. Timepoint: 3 weeks. Method of measurement: Beck Rating Scale for Depression. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Zhale Nilsaz
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed