Analgesia after orthopedic surgery for lower extremity fractures. Fracture of femur
Conditions
Interventions
Intervention 1: Control group: administration of placebo every 12 hours in patient under iv morphine pump for three days. Intervention 2: Case group: administration of gabapentin 300 mg every 12 hours
Placebo
Treatment - Drugs
Control group: administration of placebo every 12 hours in patient under iv morphine pump for three days.
Case group: administration of gabapentin 300 mg every 12 hours in patient under iv morphine pump for three days
Sponsors
Iran University of Medical Sciences (IUMS)
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients aged 20-70 years old, classified ASA physical status I–II who were candidate for orthopedic surgery on lower extremity fractures under general anesthesia. Exclusion criteria: severe uncontrolled co-existing diseases (CNS, convulsive, cardiovascular, ...), renal failure, concurrent use of anticonvulsant drug and /or other analgesic drugs, alcohol, addiction, known allergy to gabapentin or morphine, and patient refusal.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative analgesia. Timepoint: every 12 hrs. Method of measurement: Visual analoque scale, and analgesic consumption. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: every 12 hours. Method of measurement: Observation and evaluation of patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarnad Imani
Iran University of Medical Sciences
Outcome results
None listed