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Effect of hydrogen peroxide and zinc mouth-wash in reducing gingival inflammation

Effect of hydrogen peroxide and zinc mouth-wash on periodontal indices in patients with chronic gingivitis in randomized clinical trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20101006004877N29
Enrollment
64
Registered
2021-10-07
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis. Chronic gingivitis

Interventions

Intervention 1: Control group: This group is considered as a positive control group and people in this group will not use mouthwash. Intervention 2: Intervention group: People in this group are asked

Sponsors

Vice chancellor for research, Faculty of Dentistry, Isfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 64 Years

Inclusion criteria

Inclusion criteria: 15 functional teeth at least Gingivitis in gingival. ( gingival index at least 2 or more ) Don’t use alcohol and cigarettes non-existence of systemic diseases that effect gingiva condition l Don’t use drugs that effect periodontal condition Non-existence of periodontal surgery or condition that effect periodontal diseases

Exclusion criteria

Exclusion criteria: People with dental anomalies People over the age of 65 People with a history of orthodontic treatment People with a history of bleaching treatment.

Design outcomes

Primary

MeasureTime frame
Decrease in probing death. Timepoint: In the beginning of research- 2 weeks- 6 weeks- 3 months. Method of measurement: By periodontal probe in the mid buccal tooth gingival.;Plaque index. Timepoint: In the beginning of research- 2 weeks- 6 weeks- 3 months. Method of measurement: For indicating plaque index , using silness&leo plaque index . In this index , 0 demonstrative no microbial plaque , 1 demonstrative a thin layer of plaque in around of free marginal gingival, 2 demonstrative the medium amount of plaque in gingival sulcus and 3 demonstrative large amount of plaque in sulcus or periodontal pocket till free gingival margin.;Probing bleeding index. Timepoint: In the beginning of research- 2 weeks- 6 weeks- 3 months. Method of measurement: In this criterion, zero indicates the absence of bleeding, one indicates the presence of a specific bleeding point, two indicates the presence of isolated bleeding points in several cases or the presence of a single line of bleeding, three indicates that after probing the triangle between A tooth is immediately filled with blood, and a score of 4 in this index indicates heavy bleeding after probing, which immediately flows into the marginal sulcus.;Gingival index. Timepoint: In the beginning of research- 2 weeks- 6 weeks- 3 months. Method of measurement: To determine the gingivitis index (GI) of patients, the 4-part Leo & Silness criterion is used, in which zero indicates normal gingiva, one indicates mild inflammation (slight changes in color and mild edema with bleeding during probing), two indicates moderate inflammation. Along with edema redness and bleeding during probing and three also indicate severe inflammation with severe edema redness and ulceration and tendency to bleed simultaneously.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJaber Yaghini

Esfahan University of Medical Sciences

J_yaghini@dnt.mui.ac.ir+98 31 3792 5542

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026