Asthenospermia. male infertility
Conditions
Interventions
Treatment - Drugs
Control group: placebo 1g per day for 3 months + 600mg vitamin E
Intervention 1: Control group: placebo 1g per day for 3 months + 600mg vitamin E. Intervention 2: Intervention group: omega-3 fatty acids 1000mg per day for 3 months + 600mg vitamin E.
Intervention group: omega-3 fatty acids 1000mg per day for 3 months + 600mg vitamin E
Sponsors
National Nutrition Research Institute
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Willing to participate in the study and filling out the informed consent form, they should be infertile (no conception after 12 months intercourse without any contraception), age 20-45 y.o, idiopathic asthenospermia according to WHO criteria, normal hormonal profile. Exclusion criteria: any infection in genitourinary (GU) tract, any anatomical abnormality in GU tract, any chronic disease during last 3 months, any surgery in GU tract, consumption of omega-3 fatty acids and/or vitamin E supplements during last 3 months .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm motility. Timepoint: 3 months. Method of measurement: spermatogram. | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxidative stress. Timepoint: 3 months. Method of measurement: total antioxidant capacity and PGF2a. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzita Hekmatdoost, MD, PhD
National Nutrition Research Institute
Outcome results
None listed