Comparative investigation of two sedation methods during cataract surgery with two combinations of sodium thiopental and ketamine vs propofol and ketamine under local anesthesia.

A comparative study of two sedation methods during cataract surgery with two combinations of sodium thiopental and ketamine vs propofol and ketamine under local anesthesia in 60 patients who are candidates for cataract surgery due to old age and the effectiveness and side effects of this combination

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100926004819N6

Enrollment

Registered

2023-01-27

Start date

2023-01-09

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

senile cataract. Other complications of anesthesia

Interventions

Intervention 1: Intervention group: The first group, after placing the patient on the surgical bed, ambulatory monitoring of blood pressure, ECG, pulse oximetry and capnograph is established for monit

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Candidate patients for cataract surgery due to old age Consent to participate in the study Age between 30 and 70 years ASA1/2/3

Exclusion criteria

Exclusion criteria: Need general anesthesia Seizures and response to study drugs High risk of surgery such as monocular or traumatic patients History of alcoholism, smoking, drugs

Design outcomes

Primary

Measure	Time frame
Drug's side effect. Timepoint: in recovery room , after being alert. Method of measurement: questionnaire.;Appropriate sedation during surgery with monitoring of vital signs during surgery. Timepoint: 0, 10, 20, 30, 40, 60 minutes in the operating room and 0, 15, 30 minutes in recovery. Method of measurement: monitoring device.;Pain intensity during and after surgery. Timepoint: During recovery and during surgery. Method of measurement: questionnaire.;Consent of the surgeon and the patient. Timepoint: During recovery and during surgery. Method of measurement: questionnaire.	—

Measure

Time frame

Drug's side effect. Timepoint: in recovery room , after being alert. Method of measurement: questionnaire.;Appropriate sedation during surgery with monitoring of vital signs during surgery. Timepoint: 0, 10, 20, 30, 40, 60 minutes in the operating room and 0, 15, 30 minutes in recovery. Method of measurement: monitoring device.;Pain intensity during and after surgery. Timepoint: During recovery and during surgery. Method of measurement: questionnaire.;Consent of the surgeon and the patient. Timepoint: During recovery and during surgery. Method of measurement: questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaied Morteza Heidari Tabaei Zavareh

Esfahan University of Medical Sciences

fatemeh.sadat075@gmail.com+98 921 114 5026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026