Diffuse brain injury. Diffuse brain injury
Conditions
Interventions
Intervention 1: The intervention group is treated by 300 mg Gabapentin twice daily. Intervention 2: The control group is treated by placebo twice daily.
Treatment - Drugs
Placebo
The intervention group is treated by 300 mg Gabapentin twice daily
The control group is treated by placebo twice daily
Sponsors
Vice chancellery for research, Isfahan university of medical sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients who suffered from moderate (9 12) and severe (GCS<9) traumatic brain injury and diffuse axonal injury were included. The exclusion criteria were: the patient death during the study and the patients who did not tolerate gabepentin or present its severe side effects.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glasgow Coma Scale. Timepoint: before intervention, 1 and 2 weeks after intervention onset, at the first outpatient referral. Method of measurement: Physical examination.;Glasgow outcome scale. Timepoint: before intervention, 1 and 2 weeks after intervention onset, at the first outpatient referral. Method of measurement: Physical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Electroencephalography. Timepoint: before intervention, 1 and 2 weeks after intervention onset, at the first outpatient referral. Method of measurement: Electroencephalography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Ali Sonbolestan
Isfahan university of medical sciences
Outcome results
None listed