Effect of tranexamic acid on blood loss after knee arthroplasty

Effectiveness of oral tranexamic acid administration on blood loss after knee artroplasty

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201009204780N1

Enrollment

Registered

2012-02-04

Start date

2012-01-31

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee artherosis. Arthrosis

Interventions

Intervention 1: control: without a drug or placebo prescription. Intervention 2: intervention: Prescription of oral tranexamic acid two hours before surgery and every 6 hours until 18 hours after surg

Treatment - Drugs

control: without a drug or placebo prescription

intervention: Prescription of oral tranexamic acid two hours before surgery and every 6 hours until 18 hours after surgery

Eligibility

Sex/Gender

All

Age

20 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: adults’ patients undergoing knee artheroplasty. Exclusion criteria: patients with history of ischemic heart diseases, renal failure, cirrhosis, bleeding disorders and consumption of NSAID or anticoagulants.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: 12 and 24 hours after surgery. Method of measurement: bleeding in drain in milliliters.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzam Moradi Zarmehri

Mashhad University of medical sciences

moradia872@mums.ac.ir+98 51 1881 8229

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026