Disease of anus. Disease of anus and rectum, unspecified
Conditions
Interventions
Intervention 1: Intervention group: At the end of the surgery, patients in this group are injected with 1.5 µg/kg diluted dexmedetomidine with a volume of 10 cc in the perianal area. Intervention 2: C
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Class I and II ASA candidate for perianal surgery (fissures and hemorrhoids)
Exclusion criteria
Exclusion criteria: Advanced diabetes which leads to neuropathy Neuromuscular diseases Psychological and neurological diseases Drug addiction Use of analgesics or NSAIDs within the last 24 hours Pregnancy Body Mass Index is more than 23 Preoperative hearth rate is less than 45 Second or third-degree AV block Use of antihypertensive drugs including methyldopa, clonidine and other alpha 2 adrenergic agonists
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Using Visual Analogue Scale and verbal assessment on a scale of 1 to 10.;Nausea. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Clinical observations.;Vomiting. Timepoint: 1,3,6,12 and 24 hours after operation. Method of measurement: Clinical observations.;Vital signs including blood pressure and heart rate. Timepoint: Up to 24 hours after surgery. Method of measurement: Patient monitoring devices. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Alipour
Mashhad University of Medical Sciences
Outcome results
None listed