type 2 diabetes. non-Insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: 200mg/day of red grape seed extract for 8 weeks. Intervention 2: Placebo with the same dose for 8 weeks.
Treatment - Drugs
Placebo
200mg/day of red grape seed extract for 8 weeks
Placebo with the same dose for 8 weeks
Sponsors
Drug Applied Reaearch Center, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: having diabetes for at least five years, 30 to 65 years of age, voluntary consent for participation in the study, using drugs to control blood glucose and not using insulin Exclusion criteria: using antioxidant supplements in the previous three months, persons with gastric treatment, pregnant and lactating women, presence of hepatic or renal failure, hyper and hypothyroidism, celiac, diarrehea, recent surgery or acute infection, using anticoagulant drugs
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antioxidant indices. Timepoint: 8 weeks after intervention after. Method of measurement: Assessments of changes in TAC.SOD, GPX.MDA.;Lipid profiles. Timepoint: 8 weeks after intervention after. Method of measurement: laboratory.;FBS and HbA1C. Timepoint: 8 weeks after intervention. Method of measurement: laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: 8 weeks after the supplementation. Method of measurement: Sphygmometer.;Body Mass Index. Timepoint: 8 weeks after the supplementation. Method of measurement: Weight(Kg)/height(m2). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahram Pourghassem
Health and Nutrition Faculty, Tabriz University of Medical Sciences
Outcome results
None listed