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Effect of synbiotics in treatment of childhood atopic dermatitis

Effect of synbiotics in reduction scoring of childhood atopic dermatitis (SCORAD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201009094719N2
Enrollment
40
Registered
2010-12-20
Start date
2007-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atopic dermatitis. Dermatitis and eczema

Interventions

Intervention 1: In the intrvention group, children daily took one sachet containing 10 milligram mixture of 1 × 109 CFU/ of seven strain probiotics plus prebiotic (990 milligram fructo-oligosaccharide
Treatment - Drugs
In the intrvention group, children daily took one sachet containing 10 milligram mixture of 1 × 109 CFU/ of seven strain probiotics plus prebiotic (990 milligram fructo-oligosaccharides). We instruct
In the control group, children daily took one sachet for oral use ,containing 1000 milligram sucrose. similarly We instructed usual treatment of atopic dermatitis including bathing with lukewarm wat

Sponsors

Iranian Ast?ma Allergy and Immunology Research Institu
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were children aged 1–36months with moderate to severe Atopic Dermatitis (SCORAD>25). Exclusion criteria were age less than 1 month and more than 36 months, SCORAD<25, recurrent infections( as an evidence of immunodeficiency), congenital abnormality, chronic disease and problem in eating and administration of systemic corticosteroids.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sevearity of atopic dermatitis acording to SCORAD. Timepoint: befor and two months after intervention. Method of measurement: SCORAD table.

Secondary

MeasureTime frame
Adverse reaction. Timepoint: every 2 weeks. Method of measurement: asking from parents.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasood Movahedi

Tehran University of Medical Sciences and Health Services

movahedm@sina.tums.ac.ir+98 66938545

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026