Efficacy of folic acid in treatment of erectile dysfunction in men with diabetes mellitus type II

The assessment of efficacy of folic acid plus tadalafil in treatment of erectile dysfunction in men with diabetes mellitus type II

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201009054582N3

Enrollment

100

Registered

2010-10-14

Start date

2010-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erectile Dysfunction. Diseases of male genital organs

Interventions

Intervention 1: Placebo tablet, once daily for 3 months. Intervention 2: Acid folic tablet (5 mg), once daily for 3 months.

Placebo

Treatment - Drugs

Placebo tablet, once daily for 3 months

Acid folic tablet (5 mg), once daily for 3 months

Eligibility

Sex/Gender

Male

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- moderate to server Erectile Dysfunction at least 3 months (IIEF < 17). 2- Diabetes mellitus type II. 3- No history of folic acid in last 3 months. Exclusion criteria: 1- Erectile dysfunction with known psychological origin. 2- Cord injury. 3- Patients who are under treatment with folic acid. 4- Contraindication of consumption of 5-phosphodiestrase inhibitors for example history of anaphylactic reaction. 5- Hypertension. 6- Antihypertensive and antilibido drugs consumption. 7- Hyperthyroidism.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Improvement of rectile function. Timepoint: 3 months. Method of measurement: IIEF questionaire (International Index of Erectile Function).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ahmad Asadollahzadeh

Urology Research Center

asad2418@yahoo.com ; urc1384@yahoo.com+98 13 1552 5259

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026