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Comparison between clinical effects of intra-articular ozone and intra-articular steroid injection in the treatment of chronic ankle osteoarthritis

Comparison between clinical effects of intra-articular ozone and intra-articular steroid injection in the treatment of chronic ankle osteoarthritis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100827004641N19
Enrollment
40
Registered
2022-01-27
Start date
2019-09-23
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Osteoartritis of Ankle. Primary osteoarthritis, unspecified ankle and foot

Interventions

Intervention 1: Intervention group: corticosteroid injection: mixture of 40 mg of triamcinolone and 1 mg of lidocaine 2% was injected . Mortis join was the dite of injection. On the inter-maleular lin

Sponsors

Physical Medicine and Rehabilitation Research Center of Tabriz
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to No maximum

Inclusion criteria

Inclusion criteria: Existence of symptoms of ankle osteoarthritis for at least 3 months Minimum score of 3 in the criterion (VAS) Absence of inflammatory rheumatic diseases Failure to respond to conservative drug and physiotherapy treatments during the past 6 months Satisfaction of patients participating in the study rug and physiotherapy treatments during the past 6 months Aged 45 years and older

Exclusion criteria

Exclusion criteria: Severe osteoarthritis (Grade 4 candidates for joint replacement surgery) Rumatic disease Clearly visible deformity of the ankle Ankylosis Ozone contraindications include: -Hyperthyroidism -Thrombocytopenia -Pregnancy Recent history of heart attack G-6PD deficiency Definitive and relative contraindications to steroid injections include: Bacteremia, sepsis, intra-articular or pre-uricular infection, history of post-injection allergies Specific skin lesion at the injection site

Design outcomes

Primary

MeasureTime frame
The amount af Reduce in pain after injection. Timepoint: 1 month after injection and 6 months after injection. Method of measurement: FADI questionnaire.

Secondary

MeasureTime frame
Improvement of function and reduce in pain of ankle. Timepoint: Before,1 month an 6 months after injection. Method of measurement: FADI questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBina Eftekharsadat

Tabriz University of Medical Sciences

binasadat@gmail.com+98 41 1336 4672

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026