Comparison of the effect of ozone, corticosteroid and prolotherapy in coccydynia

Comparison of the effect of ultrasound-guided topical ozone injection, corticosteroid injection and prolotherapy on pain intensity in patients with coccydynia: A prospective, double-blind, multicenter randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100827004641N17

Enrollment

Registered

2020-08-26

Start date

2020-01-18

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coccydynia. Sacrococcygeal disorders, not elsewhere classified

Interventions

Intervention 1: Intervention group one: Ozone (O2-O3), 12 micro-gram, one time ultrasound guided injection inside the sacrococcygeal area. Intervention 2: Intervention group two: Corticosteroid, 40

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Diagnosis of coccydynia Age of 18-65 years Pain score ranging from 1 to 10 in visual analogue scale

Exclusion criteria

Exclusion criteria: Tumors of the cauda equina Pelvic surgery Herniation of the lumbosacral disc

Design outcomes

Primary

Measure	Time frame
Pain intensity. Timepoint: Evaluating the visual analogue scale at the beginning of the study (before intervention) and 7 and 60 days after injection. Method of measurement: Visual analogue Scale.;Overall recovery rate. Timepoint: Evaluating the overall recovery rate at 7 and 60 days after injection. Method of measurement: Patient Global Impression of Improvement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBina Eftekharsadat

Tabriz University of Medical Sciences

binasadat@tbzmed.ac.ir+98 41 1330 3193

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026