Benign Prostatic Hyperplasia. Hyperplasia of prostate
Conditions
Interventions
Transurethral injection of Botulinum in prostate.
Treatment - Other
Transurethral injection of Botulinum in prostate
Sponsors
Vice chancellor for research of Guilan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
50 Years to 149 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: male patients older than 50 years, patients with BPH refractory to medical therapy and not suitable for surgery, IPSS (International Prostatic Symptom Score) =8. Exclusion criteria: active UTI, previous history of prostate surgery, prostate cancer, acute prostatitis, simultaneous use of drugs such as: Amino glycosides, Cholinergics, Anticholinergics, Androgens, Estrogen, Steroids, history of allergy to BoNT-A, neurologic disease like Parkinson, Myastenia Gravis, Multiple Sclerosis, history of allergy to BoNT.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| International score of prostatic signs & symptoms. Timepoint: before intervention and 3 months after that. Method of measurement: IPSS: International Prostatic Symptom Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Maximum urinary flow. Timepoint: before intervention and 3 months after that. Method of measurement: uroflometry.;Prostate volume. Timepoint: before intervention and 3 months after that. Method of measurement: sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ahmad Enshaei
Urology Research Center
Outcome results
None listed