Erectile dysfunction. Male erectile dysfunction
Conditions
Interventions
Intervention 1: Intervention group: A tourniquet will be placed at the proximal end of the penis. An injection of 100 units of onabotulinumtoxin A will be performed by diluting 500 units of Mosport in
Sponsors
Urology Research Centre, Guilan University of Medical Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Patients with vasculogenic ED resistant to first-line drug therapy with PDE5Is who do not want second- and third-line treatment.
Exclusion criteria
Exclusion criteria: History of severe cardiovascular disease that interferes with sexual activity History of mental illnesses and disorders The presence of anatomical abnormalities that significantly impair erectile function The presence of hormonal abnormalities that significantly impair erectile function The presence of neurological abnormalities that significantly impair erectile function History of radical pelvic surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Erectile function. Timepoint: Before intervention, 1, 3 and 6 months after injection. Method of measurement: The International Index of Erectile Dysfunction (IIEF) questionnaire.;Erection quality. Timepoint: Before intervention, 1, 3 and 6 months after injection. Method of measurement: Erectile Hardness Score (EHS) index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction score of treatment. Timepoint: 1, 3 and 6 months after last injection. Method of measurement: Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS).;Complications after injection. Timepoint: From the day of injection to 6 months after injection. Method of measurement: Interview and examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaber Khajavi
Urology Research Center, Guilan University of Medical Sciences
Outcome results
None listed