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The effect of general anesthesia on tonsillectomy

Comparison the effect of propofol and sodium thiopental on post-extubation laryngospasm in patients undergoing tonsillectomy.

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201008164578N1
Enrollment
60
Registered
2010-11-07
Start date
2004-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Enlargment of tonsils. Condition 2: General Anesthesia in tonsillectomy. Hypertrophy of tonsils -

Interventions

Intervention 1: In control group (Thiopental), for premedication used Diazepam 0.05 mg/kg and Fentanyl 1microgram/kg and atropine 20 microgram/kg. For induction of anaesthesia in this group used Thiop
Treatment - Drugs
In control group (Thiopental), for premedication used Diazepam 0.05 mg/kg and Fentanyl 1microgram/kg and atropine 20 microgram/kg. For induction of anaesthesia in this group used Thiopental 5mg/kg
In intervention group (propofol), for premedication used Diazepam 0.05 mg/kg and Fentanyl 1microgram/kg and atropine 20 microgram/kg. For induction of anaesthesia in this group used Propofol 2/5mg/kg

Sponsors

Qazvin university of medical sciences-vice chancellor for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children in 3-12 years old and ASA class 1 exclusion criteria: 1- History of common cold and sore throat in the 5 weeks prior to the study 2- History of corticosteroid usage. 3- The presence of upper and lower respiratory tract infection. 4- The presence of abnormality in the airways. 5- intubation attempt failed twice or more

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Laryngospasm. Timepoint: Laryngospasm is visualized in the end of surgery and after extubation of patient. Method of measurement: Patient were divided in four groups: 1-without laryngospasm 2-mild laryngospasm 3-moderate laryngospasm4-sever laryngospasm.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026