Comparative evaluation of low-power laser and co2 laser in treatment of oral lichen planus.

Comparative evaluation of low-power laser and co2 laser in treatment of patients with oral lichen planus presenting to the oral Medicine Department at the Dentistry faculty in Tehran University of Medical Sciences in 1388-1389.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201008161559N4

Enrollment

Registered

2010-09-12

Start date

2009-04-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lichen planus. lichen planus

Interventions

Intervention 1: Low power laser including red light (?=633 nm, light exposure dose=0.3 J/cm2) and infrared light (?=830 nm, light exposure dose=0.3 J/cm2) every other day for 5 sessions. Intervention

Treatment - Other

Low power laser including red light (?=633 nm, light exposure dose=0.3 J/cm2) and infrared light (?=830 nm, light exposure dose=0.3 J/cm2) every other day for 5 sessions

Co2 laser (?=10600 nm, 20 W) at one session.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: clinical and histopathologic diagnosis of lichen planus with clinical criteria, consisting of the presence of symmetric reticular or papular lesions with or without erosive-atrophic components. Histopathologic features of oral lichen planus are: 1) Areas of hyperparakeratosis or hyperorthokeratosis, often with a thickening of the granular cell layer and a saw-toothed appearance to the retepages. 2) Liquefaction degeneration or necrosis of the basal layer. 3) A dense subepithelial band, shaped by infiltration of lymphocytes T and macrophages. 4) Absence of dysplastic changes. Exclusion criteria: Using drugs (including for the treatment of lichen planus at the first session) and exposure to amalgam fillings.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Size of lesions. Timepoint: 2 weekly in the first month and then monthly for 3 months. Method of measurement: size of lesions with scaled tongue blade.;Pain and discomfort in the oral lesions. Timepoint: 2 weekly in the first month and then monthly for 3 months. Method of measurement: VAS.;Clinical score. Timepoint: 2 weekly in the first month and then monthly for 3 month. Method of measurement: Registration the primary scores of lesions and their changes on the follow up period as described in the material and method.	—

Measure

Time frame

Size of lesions. Timepoint: 2 weekly in the first month and then monthly for 3 months. Method of measurement: size of lesions with scaled tongue blade.;Pain and discomfort in the oral lesions. Timepoint: 2 weekly in the first month and then monthly for 3 months. Method of measurement: VAS.;Clinical score. Timepoint: 2 weekly in the first month and then monthly for 3 month. Method of measurement: Registration the primary scores of lesions and their changes on the follow up period as described in the material and method.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Elham Moslemi

Oral Medicine Department, Tehran University of Medical Sciences

dr.emoslemi@yahoo.com+98 21 8838 4235

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026