Effectiveness of intravenous Dexamethasone versus Propofol for pain relief in Migraine headache in the Emergency Department in Imam Reza Hospital, Tabriz University of Medical Science.

Effectiveness of intravenous Dexamethasone versus Propofol for pain relief in the Migraine headache in the Emergency Department in Imam Reza Hospital, Tabriz University of Medical Science.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201008122496N4

Enrollment

Registered

2010-10-15

Start date

2009-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine headache. common migraine

Interventions

Intervention 1: Intravenous Propofol 10-20 mg every 3 -5 minutes. Intervention 2: Intravenous Dexamethasone approximately 0.15 mg/kg slowly.

Treatment - Drugs

Intravenous Propofol 10-20 mg every 3 -5 minutes

Intravenous Dexamethasone approximately 0.15 mg/kg slowly

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: A. At least five attacks fulfilling the criteria in B, C, D, and E. B. Attack lasts 4 to 72 hours with or without treatment. C. Headache has at least two of the following characteristics: 1. Unilateral location 2. Pulsating quality 3. Moderate to severe intensity 4. Aggravated by walking up stairs or similar routine physical activity D. During headache, at least one of the following: 1. Nausea or vomiting (or both) 2. Photophobia and phonophobia E. History, physical. and neurologic examination and, if appropriate, diagnostic tests to exclude related organic disease. Exclusion criteria: 1-Patients who received narcotic, triptans or other vasoconstrictors like intravenous dihydroergotamine 2- Allergy to eggs or soya

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: at 5, 10,20,30 and 45th minutes following intervention. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Hassan Soleimanpour

Tabriz University of Medical Sciences

h_mofid1357@yahoo.com+98 41 1335 2078

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 25, 2026