Evaluation of NAC for prevention of post ERCP pancreatitis: a prospective double blind randomized pilot study

EVALUATION OF N ACETYL CYCTEIN IN PREVENTION OF POST ERCP PANCRETITIS: A DOUBLE BLIND randomized PILOT STUDY

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201008094545N1

Enrollment

100

Registered

2012-12-23

Start date

2010-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post ERCP pancreatitis. other acute pancreatitis

Interventions

Intervention 1: NAC 1200mg in 150 cc water. Intervention 2: 150cc water.

Prevention

Placebo

NAC 1200mg in 150 cc water

150cc water

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: every patient candidate for ERCP in GI ward of Ahwaz Imam hospital except those with preexisting pancreatitis or uncontroled diabetes melitus

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Serum lipase. Timepoint: before and after ERCP. Method of measurement: level of enzyme in serum.;Serum amylase. Timepoint: before and 24 hours after ERCP. Method of measurement: measurement of enzyme level in serum.	—

Secondary

Measure	Time frame
Incidence of pancreatitis. Timepoint: 24 hours after ERCP. Method of measurement: enzyme level in serum.;Abdominal pain. Timepoint: after ERCP. Method of measurement: to be or not to be.;Duration of addmision. Timepoint: how long. Method of measurement: how many days.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Pezhman Alavi nejad

AhwazJdi Shapur medical univercity

palavinezhad@yahoo.comehajiani@ajums.ac.irelhamkarimi246@gmail.com+98 61 1391 2533

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026