Benighn Prostatic Hypertrophia. Benign Prostatic Hypertrophia
Conditions
Interventions
Placebo
Treatment - Drugs
Placebo tablet at 10 pm every night for 12 weeks
Tadalafil tablet 10mg at 10 pm every night for 12 weeks
Intervention 1: Placebo tablet at 10 pm every night for 12 weeks. Intervention 2: Tadalafil tablet 10mg at 10 pm every night for 12 weeks.
Sponsors
Guilan University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with score > 8 and without any indications for prostatic surgery such as recurrent retention, persistent gross hematuria, permanent urinary infections associated with BPH, renal function failure and hydronephrosis, bladder stone due to BPH, under previous standard medical treatment with prazocine (max doze 10mg) daily with or without Finastride (5 mg, daily, for 3 months). Response to medication should be in plateau level
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| International score of prostatic signs & symptoms. Timepoint: Baseline and 3 months after the intervention. Method of measurement: IPSS: International Prostatic Symptom Score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary satisfaction. Timepoint: Baseline and 3 months after the intervention. Method of measurement: (IPSS: International Prostatic Symptom Score).;Maximum urinary flow. Timepoint: Baseline and 3 months after the intervention. Method of measurement: Uroflometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Amin Afshari Moghaddam
Urology Research Center
Outcome results
None listed