Polycystic ovarian syndrome. Endocrine nutritional and metabolic diseases
Conditions
Interventions
Intervention 1: Metformin 500 mg three times dialy, orally for 3 month. Intervention 2: Pioglitazone 30 mg dialy, orally for 3 months.
Treatment - Drugs
Metformin 500 mg three times dialy, orally for 3 month.
Pioglitazone 30 mg dialy, orally for 3 months
Sponsors
Vice-chancellor for research, Kermanshah University of Medical Science
Eligibility
Sex/Gender
Female
Age
20 Years to 49 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: High TSH with FT4 in normal range Exclusion criteria: receiving Levothyroxine, glucocorticoids, aspirin, amiodaron, lipid lowering agents, OCP, dopamine antagonist eg. metoclopramide and domperidone in recent 6 months, diabetic patients, pregnant women, women in menopause ages, patients older than 60 years
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: 3 months. Method of measurement: Barometers.;Fasting sugar serum level. Timepoint: 3 months. Method of measurement: mg/dl.;Fasting Insulin serum level. Timepoint: 3 months. Method of measurement: Uiu/ml.;Testostrone serum level. Timepoint: 3 months. Method of measurement: ngr/dl.;DHEADS serum level. Timepoint: 3 months. Method of measurement: ngr/dl. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cholesterol serum level. Timepoint: 3 months. Method of measurement: mg/dl.;Triglyceride serum level. Timepoint: 3 months. Method of measurement: mg/dl.;LDL serum level. Timepoint: 3 months. Method of measurement: mg/dl.;HDL serum level. Timepoint: 3 months. Method of measurement: mg/dl. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Karoon Shahebrahimi
Kermanshah University of Medical Sciences
Outcome results
None listed