Non-insulin-dependent diabetes mellitus. Malnutrition-related diabetes mellitus
Conditions
Interventions
Intervention 1: Tocomas added to canola oil (525 mg Tocomas per 15 gram canola oil), substitution with daily oil consumption, for 8 weeks. Intervention 2: canola oil (15 gram) substitution with daily
Prevention
Tocomas added to canola oil (525 mg Tocomas per 15 gram canola oil), substitution with daily oil consumption, for 8 weeks
canola oil (15 gram) substitution with daily oil consumption, for 8 weeks
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Being volunteer or Wishing to attend, 35-60 y old, diagnosed with type 2 diabetes for at least 1 year (FPG = 126 mg/dl or 2hPG = 200 mg/dl), BMI = 40 kg/m2, no cancer or thyroid or liver disease Exclusion criteria: Taking insulin, Changing medication dosage or physical activity level 2 mo before or during the study, Pregnancy, lactation, dialysis, Using multivitamins, minerals, or other antioxidants during 1 month prior to the study, Using warfarins or other anticoagulant drugs
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase Total Antioxidant Capacity (TAC). Timepoint: 8 weeks. Method of measurement: Spectrophotometery.;Decrease nitric oxide (NO). Timepoint: 8 weeks. Method of measurement: colorimeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting Insulin. Timepoint: 8 weeks. Method of measurement: RIA.;HOMA Index. Timepoint: 8 weeks. Method of measurement: Calculation.;High sensitivity C-reactive protein (hs-CRP). Timepoint: 8 weeks. Method of measurement: Immunoturbidimetry. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed