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The effect of erythropoietin on the erythropoiesis

The effect of early erythropoietin administration on erythropoiesis in preterm infants

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201008091380N2
Enrollment
44
Registered
2010-10-30
Start date
2010-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaemia of prematurity. Anaemia of prematurity

Interventions

Intervention 1: Infants in control group don’t receive placebo. Control infants receive 3 mg/kg/day elemental iron once a day enterally. In all infants minimal the enteral intake at the end of first w
Prevention
Infants in control group don’t receive placebo. Control infants receive 3 mg/kg/day elemental iron once a day enterally. In all infants minimal the enteral intake at the end of first week of age is 50
Treated infants receive 500 u/kg/wk rhu EPO, 2 times weekly, administer subcutaneously in lateral side of thight. Treatment continue untile 4 weeks after beginning. Criteria for withholding / stopping

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: premature infants with birth weight 40% head box oxygen or dependent on mechanical ventilation, systolic blood pressure > 100mm Hg , an absolute neutrophil counts (ANC) of = 500/µl.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hematocrit. Timepoint: at the beginning and end of study. Method of measurement: with colter counter.

Secondary

MeasureTime frame
Pack cell transfusion. Timepoint: at the end of study. Method of measurement: ml.;Ferritin. Timepoint: begining and end of study. Method of measurement: Radioimunoassay.;Reticulocyte. Timepoint: begining and end of study. Method of measurement: Microscope.;Mean daily weight gain. Timepoint: begining and end of study. Method of measurement: Weigher.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNoori-Shakam M.

Kerman University of Medical Sciences

noori@ssu.ac.ir+98 34 1322 2269

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026