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Effect of adding lidocaine to morphine for pain control after cesarean section

Effect of adding lidocaine to Patient Controlled Analgesia (PCA) with morphine on pain intensity after cesarean section with spinal anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100713004365N23
Enrollment
80
Registered
2018-09-22
Start date
2018-10-17
Completion date
Unknown
Last updated
2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: For patients in the intervention group, the PCA solution contain 50 ml of 2% lidocaine with 30 mg (3 ml) of morphine in 47 mL of normal saline (total volume 100 ml)

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: The patient's willingness to participate in the study and obtain informed consent Candidate for non-emergency cesarean section with spinal anesthesia Age between 45 and 20 years Class I of American Society of Anaesthesiologists (ASA) physical status Body mass index (BMI) less than 40 Parity 1 or 2

Exclusion criteria

Exclusion criteria: Known sensitivity to lidocaine or bupivacaine History of previous intra abdominal surgery Multiple pregnancy Pre-operative acute pain History of substance abuse and psychotropic drugs consumption Unwillingness to perform spinal anesthesia

Design outcomes

Primary

MeasureTime frame
Pain intensity after surgery. Timepoint: 2, 4, 6, 12, 18 and 24 hours after surgery. Method of measurement: Visual analogue scale.

Secondary

MeasureTime frame
Satisfaction with pain control. Timepoint: 24 hours after intervention. Method of measurement: Visual Analogue Scale.;Nausea. Timepoint: 2, 4, 6, 12, 18 and 24 after surgery. Method of measurement: Visual Analogue Scale.;Length of hospital stay. Timepoint: Discharge from the hospital. Method of measurement: Patients record.;Amount of drug consumed through morphine pump. Timepoint: 24 hours after intervention. Method of measurement: Patients record.;Return of normal bowel function. Timepoint: During the time of study. Method of measurement: Patients record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Gholipour Baradari

Sari University of Medical Sciences

gholipourafshin@yahoo.com+98 11 3336 1702

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026