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The effect of melatonin on anxiety before hysterectomy

Investigating the effect of melatonin on reducing preoperative anxiety in abdominal hysterectomy; a double blinded clinical trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100707004345N6
Enrollment
80
Registered
2019-04-11
Start date
2019-05-05
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety before abdominal hysterectomy surgery. Reaction to severe stress and adjustment disorders

Interventions

Intervention 1: Intervention group: The group receiving lorazepam + Melatonin: Dosage of Melatonin for patients will be 6 milligrams based on previous studies. (3 milligrams tablets are available on t

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for elective abdominal hysterectomy Aged 30-65

Exclusion criteria

Exclusion criteria: Major surgery for the past three years Chronic health problems like diabetes, cardiovascular disease Mood disorders (anxiety) that are under medication Addiction Malignant problems that cause hysterectomy Emergency hysterectomy

Design outcomes

Primary

MeasureTime frame
Patient's anxiety before surgery. Timepoint: Before prescribing the drug, when patients enter the operating room and before the anesthetic induction. Method of measurement: Visual Aualogue scale.

Secondary

MeasureTime frame
Blood pressure. Timepoint: Before prescribing the drug, when patients enter the operating room and before the anesthetic induction. Method of measurement: Manometer.;Heart rate. Timepoint: Before prescribing the drug, when patients enter the operating room and before the anesthetic induction. Method of measurement: Monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mirmansouri

Rasht University of Medical Sciences

a_mirmansoori@gums.ac.ir+98 13 1666 9064

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026