comparison of 10- and 30-min CXL in Down patients

Comparison of effect of Accelerated and Standard Corneal Cross-linking in Down Syndrome keratoconic patients: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100706004333N3

Enrollment

Registered

2018-07-10

Start date

2018-07-23

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Progressive keratoconus in Down syndrome patients. Keratoconus in Down syndrome

Interventions

Intervention group: 10-minutes cross-linking will be perform for one eye of bilateral keratoconic patients under general anesthesia..

Eligibility

Sex/Gender

All

Age

10 Years to 30 Years

Inclusion criteria

Inclusion criteria: definite Down syndrome Progressive keratoconus age 10-30 years old minimum cooperation for imaging

Exclusion criteria

Exclusion criteria: concurrent intellectual disability such as Autism or Klinefelter History of ophthalmic surgery corneal pathology such as Pterygium

Design outcomes

Primary

Measure	Time frame
Corneal biomechanics. Timepoint: before and one-year after surgery. Method of measurement: Corneal Visualization Scheimpflug Technology (Corvis-ST; Oculus Optikgeräte GmbH, Germany).;Corneal keratometry. Timepoint: Before and one-year after surgery. Method of measurement: Pentacam (Oculus Optikgeräte GmbH, Wetzlar, Germany).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheila Asgari

Noor Eye Hospital

soheilaasgari@gmail.com+98 21 8865 1515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 17, 2026