Breast density.
Conditions
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Female gender Age over 40 years
Exclusion criteria
Exclusion criteria: Suspicion of malignancy Used of drugs that affect metabolic status, such as weight, glucose, and lipid-lowering agents During the study or three months before the study History of breast cancer Proven or suspected pregnancy and lactation during the intervention Other medical conditions, such as cardiovascular disease, epilepsy, renal or hepatic disorders Contraindications for metformin use (such as hypersensitivity to biguanides, acidemia, heart disease, alcohol consumption, gastroparesis, hepatic disease, hyperthyroidism or hypothyroidism, severe iron deficiency anemia, renal impairments) History of unwanted and intolerable side effects of metformin (such as abdominal pain, chest pain, chills, cholestasis, diarrhea, dizziness, increased liver enzymes, severe headache, hepatitis, hypoglycemia, megaloblastic anemia, myalgia, nausea, Palpitations, rash, rash, vomiting) Suffering from hormonal disorders and metabolic diseases such as hypo or hyperthyroidism, metabolic syndrome, diabetes, severe hyperlipidemia, galactorrhea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Breast density. Timepoint: At the beginning of the study (before the intervention) and six months after the intervention. Method of measurement: Mammography scan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSadaf Alipour
Tehran University of Medical Sciences
Outcome results
None listed