major depression disorder. Major depressive disorder, recurrent
Conditions
Interventions
Intervention 1: Intervention group: Repetitive transcranial magnetic stimulation. Intervention 2: Control group: Sham repetitive transcranial magnetic stimulation.
Sponsors
Atieh Clinical Neuroscience Center
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Outpatients male and female with the range of 18-70 years of age The diagnosis of Major depressive disorder according to DSM-V Having BDI>14 Having stable symptoms as defined by not requiring a change in medication for at least 4 weeks Completion of consent form Being under supervision of a psychiatrist
Exclusion criteria
Exclusion criteria: The history of rTMS treatment for any reason Cardiac pacemaker The risk of seizure with any reasons Pregnancy High risk of suicide Intracranial implant and other ferromagnetic materials close to the head co-morbidity with disorders in axis I and II
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anhedonia. Timepoint: baseline, ten session. Method of measurement: Snaith-Hamilton Pleasure Scale (SHAPS).;Rumination. Timepoint: baseline, ten session. Method of measurement: Ruminative Response Scale (RRS).;Anhedonia network. Timepoint: baseline, ten session. Method of measurement: EEG.;Default mode network. Timepoint: baseline, ten session. Method of measurement: EEG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of depression. Timepoint: baseline, ten session. Method of measurement: Hamilton Depression Rating Scale.;Score of anxiety. Timepoint: baseline, ten session. Method of measurement: Hamilton Anxiety Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Kazemi
Atieh Clinical Neuroscience Center
Outcome results
None listed