Comparison of maintenance anesthesia with isoflurane or sevoflurane in neonates and infants during surgery

Comparison of anesthesia maintenance with Isoflurane or Sevoflurane with Laryngeal mask during minor surgery in newborns and infants

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100527004041N23

Enrollment

Registered

2021-07-25

Start date

2021-09-23

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of hemodynamic changes after anesthesia with sevoflurane and isoflurane.. Other complications of anesthesia

Interventions

Intervention 1: Intervention group: 34 infants are placed under anesthesia with 1.5% isoflurane in a mixture of 50% oxygen and 50% N2O, and hemodynamic changes are carefully monitored. Intervention 2:

Eligibility

Sex/Gender

All

Age

1 Days to 1 Years

Inclusion criteria

Inclusion criteria: Infants under one year of age candidates for elective surgery less than one hour

Exclusion criteria

Exclusion criteria: Requires endotracheal intubation for surgery Underlying cardiovascular disease

Design outcomes

Primary

Measure	Time frame
Systolic and diastolic blood pressure. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Mercury barometer.;Heart rate. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Counting in each minutes.;Saturation of peripheral oxygen. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Via the Pulse Oximeter.;Nausea and vomiting. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Visual Analogue Scale.	—

Measure

Time frame

Systolic and diastolic blood pressure. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Mercury barometer.;Heart rate. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Counting in each minutes.;Saturation of peripheral oxygen. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Via the Pulse Oximeter.;Nausea and vomiting. Timepoint: From the beginning of anesthesia to 30th minute,every 5 minutes and after that every 15minutes and in recovery section until discharging,every 10 minutes. Method of measurement: Visual Analogue Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahin Seyedhejazi

Tabriz University of Medical Sciences

seidhejazie@tbzmed.ac.ir+98 41 3526 2255

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026