ulcerative colitis. Ulcerative colitis, unspecified
Conditions
Interventions
Intervention 1: Intervention group: After calculating the amount of calories needed by each person using the Meflin formula, a diet with 75% of the calories needed to maintain weight is set based on t
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Samples with inflammatory bowel disease confirmed by histopathology The duration of the disease is less than two years The disease is active in a mild to moderate stage (diagnosis of the severity of the disease is the responsibility of the treating physician) Not consuming alcohol and drugs Not suffering from other diseases and intestinal disorders, known autoimmune diseases, cancer, inflammatory and infectious diseases Not using multivitamin-mineral, omega-3, polyphenolic and antioxidant supplements, probiotics as well as the non-use of anticoagulants such as heparin and warfarin, NSAIDs such as ibuprofen, aspirin and diclofenac, antihistamines and calcium channel antagonists such as nifedipine in the past month BMI over 18.5 and under 30 Age 18 years and above No change in the type and dosage of the drug consumed during the past month Not having clinically diagnosed psychiatric disorders that impair the patient's ability to provide written informed consent Willingness to participate in the study
Exclusion criteria
Exclusion criteria: Recurrence of the disease in a way that leads to the hospitalization of the patient Suffering from other diseases such as biliary disease, kidney diseases, known autoimmune diseases, cancer and liver disorders The presence of abscesses or abdominal fistulas A history of ileostomy and colostomy Pregnancy or breastfeeding in women or Using birth control pills Receiving tube or intravenous feeding Following special diets and vegetarianism during the last 3 months Unwillingness to continue cooperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum hs-CRP. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;TNF-a. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;TAC. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Elisa.;Life Quality. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire.;Disease Activity Index. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the first of research and end of research( 6th week). Method of measurement: scale.;BMI. Timepoint: At the first of research and end of research( 6th week). Method of measurement: Calculation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzita Hekmatdoost
Shahid Beheshti University of Medical Sciences
Outcome results
None listed