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Clinical and radiographic evaluation of applying 1.2% Atorvastatin gel with plasma rich in growth factor (PRGF) for treatment of class II furcation involvement

Clinical and radiographic evaluation of applying 1.2% Atorvastatin gel with plasma rich in growth factor (PRGF) for treatment of class II furcation involvement

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20100427003813N7
Enrollment
24
Registered
2018-05-17
Start date
2017-05-27
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

furcation grade 2 involvement of lower jaw molars.

Interventions

Intervention 1: intervention group 1: Using Atorvastatin1.2% alone in treatment of 6 mandibular molar grade II furcation involvment. Intervention 2: Intervention group 2: use of Atorvastatin1.2% plus

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with moderate to severe chronic periodontitis with severe grade II fractures on the buccal or lingual side of the first or second mandibular molars The horizontal probing depth of the probes in the affected areas is greater than or equal to 3mm

Exclusion criteria

Exclusion criteria: Systemic disease The need for prophylactic antibiotics to prevent bacterial endocarditis Use of intermittent drugs with periodontal improvement smoking presence of contraindication for periodontal surgery dental anatomical complications such as accessory canal concavity CEP, bifurcation ridge Tooth mobility more than Grade II The presence of decay and filling in the area of ??forcation There is evidence of periapical pathology in the clinical or radiographic view of the tooth Possibility of unaccompanied consent after initial periodontal treatment

Design outcomes

Primary

MeasureTime frame
Grade 2 furcation involvement of lower jaw molars. Timepoint: Immediately before surgery 3 and 6 months after surgery. Method of measurement: periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Jenabian

Babol University of Medical Sciences

n.jenabian@mubabol.ac.ir+98 11 1229 1408

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026