Evaluation of the effect of plasma rich in growth factors (PRGF) with sub- epithelial connective tissue graft via semilunar technique in dark triangle treatment

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100427003813N11

Enrollment

Registered

2020-03-29

Start date

2020-01-15

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession. Gingival recession

Interventions

Intervention 1: Intervention group: Connective tissue graft with PRGF via Semilunar technique. Intervention 2: Control group: Connective tissue graft via Semilunar technique.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years At least one region of an absence of papilla should be sub-type I, II of Tarnow's classification and in the Anterior Maxilla Ability to maintain proper good oral hygiene (O'LEARY plaque score<=20%) Signature of consent form

Exclusion criteria

Exclusion criteria: Pregnancy Coagulation problems Medications interfering with Platelet function (NSAIDs) Medications interfering with wound healing (Corticosteroid, anti-cancer) Any systemic or local disease that has a contraindication in periodontal treatment Allergic reaction to materials used in surgery Active infectious disease (hepatitis, tuberculosis and AIDS) smoking Frenum stretch in the surgical area Orthodontic patients The use of medications that are well-established causes of gingival enlargement Use of traumatic tooth brushing, abrasive tooth brushes Use of antibiotics in the past 3 months (for 2 weeks) Periodontal disease

Design outcomes

Primary

Measure	Time frame
Healing index. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with healing index (HI) based on Landry index.;Probing pocket depth (PPD). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;Esthetic Visual Analogue scale. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale.;Postoperative pain. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale.;Bleeding on probing (BOP). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;Mesiodistal distance of dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;?Apicocoronal distance of the dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.	—

Measure

Time frame

Healing index. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with healing index (HI) based on Landry index.;Probing pocket depth (PPD). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;Esthetic Visual Analogue scale. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale.;Postoperative pain. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale.;Bleeding on probing (BOP). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;Mesiodistal distance of dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.;?Apicocoronal distance of the dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Jenabian

Babol University of Medical Sciences

n.jenabian@mubabol.ac.ir+98 11 3220 7918

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026