Comparison of the Clinical, histologic and histomorphometric of Ceno Bone ® with and without plasma rich growth factor in dental socket

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20100427003813N10

Enrollment

Registered

2019-03-28

Start date

2018-09-23

Completion date

Unknown

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention 1: Intervention group: open flap debridement with plasma-rich growth factor. Intervention 2: Control group: Open flap debridement.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with non-restoring molar in the lower jaw with indications out volunteer for performing implant have good health availability for follow-up Signature of consent form

Exclusion criteria

Exclusion criteria: Patients who are not able to perform surgery smoker Pregnancy Dental Infection Patients with gingivitis or active untreated periodontitis Patients with ankylosis of teeth teeth with dehiscence Diseases that affect tissue repair Patients with certain systemic problems

Design outcomes

Primary

Measure	Time frame
Vertical changes in dental apicoronal socket. Timepoint: before surgery,5 months after surgery. Method of measurement: stent.;Degree of inflammation. Timepoint: 5 months after surgery. Method of measurement: histology.;Trabecular thickness. Timepoint: 5 months after surgery. Method of measurement: histology.;Bone-biomaterial contact. Timepoint: 5 months after surgery. Method of measurement: histology.;Presence or absence of connective tissue in the reconstructed area. Timepoint: 5 months after surgery. Method of measurement: histology.;Percentage of remnant particles. Timepoint: 5 months after surgery. Method of measurement: histology.;Percentage of new bone formation. Timepoint: 5 months after surgery. Method of measurement: histology.;Number of blood vessels. Timepoint: 5 months after surgery. Method of measurement: histology.;Bone Vitality. Timepoint: 5 months after surgery. Method of measurement: histology.;Foreign body reaction. Timepoint: 5 months after surgery. Method of measurement: histology.	—

Measure

Time frame

Vertical changes in dental apicoronal socket. Timepoint: before surgery,5 months after surgery. Method of measurement: stent.;Degree of inflammation. Timepoint: 5 months after surgery. Method of measurement: histology.;Trabecular thickness. Timepoint: 5 months after surgery. Method of measurement: histology.;Bone-biomaterial contact. Timepoint: 5 months after surgery. Method of measurement: histology.;Presence or absence of connective tissue in the reconstructed area. Timepoint: 5 months after surgery. Method of measurement: histology.;Percentage of remnant particles. Timepoint: 5 months after surgery. Method of measurement: histology.;Percentage of new bone formation. Timepoint: 5 months after surgery. Method of measurement: histology.;Number of blood vessels. Timepoint: 5 months after surgery. Method of measurement: histology.;Bone Vitality. Timepoint: 5 months after surgery. Method of measurement: histology.;Foreign body reaction. Timepoint: 5 months after surgery. Method of measurement: histology.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Jenabian

Babol University of Medical Sciences

n.jenabian@mubabol.ac.ir+98 11 3220 7918

Outcome results